Tag Archives: ageing

astaxanthin

Astaxanthin – The King of Antioxidants

Allow me to acquaint you with one of nature’s most potent antioxidants – astaxanthin (as-ta-xan-thin) – with the latest research showing promising results for those everyday concerns such as ageing skin, low immunity, tiredness and fatigue, aching joints, low fertility, poor cognitive function, below-par exercise performance – and so much more.

What is astaxanthin?

Astaxanthin is a bright red carotenoid pigment (natural colour) derived from haematococcus pluvialis (H. pluvialis), an algae with the highest levels of astaxanthin, accumulated to protect itself in response to stressors from its environment, such as starvation, high levels of salt, high temperature and radiation. The accumulation of astaxanthin turns the algae from green to red, and is responsible for the bright pink-red colouring of many marine animals such as salmon, crab and lobster and the brightly coloured feathers of flamingos, who obtain astaxanthin through their diet. Aside from its wonderful colouring, its main action is that of an antioxidant and, as such, providing protection to algae from environmental stressors as listed above.

Just as with algae, the human body is also exposed to environmental stressors; however, these lead to the creation of free radicals – for example, from factors such as poor diet, pollution, stress, exercise, smoking, alcohol and medication. Fortunately, the body has its own inbuilt antioxidant capabilities which it works hard to keep in balance. Issues arise, however, when an over-burdened body struggles to keep up, which can lead to oxidative stress and, in turn, cellular damage. Long term, oxidative stress is associated with chronic inflammation, autoimmune conditions, accelerated ageing and hormonal issues.

Astaxanthin can support combat against free radicals

Astaxanthin works in several ways to help to combat free radicals in the human body. Like all antioxidants, astaxanthin donates a chemical group to free radicals (compounds that have lost a chemical group and without it become unstable and lead to oxidative damage). With many antioxidants, they themselves can become pro-oxidant unless they are recycled by another antioxidant. Astaxanthin, importantly, has an unlimited ability to provide chemical groups without itself becoming a pro-oxidant. Astaxanthin also works by calming free radicals, absorbing the negative energy they emit. Finally, its unique chemical structure enables it to act through the entire cell, unlike fat-soluble antioxidants that tend to provide protection to the inner wall of the cell membrane, and water-soluble antioxidants that provide protection only to the outer wall. Since astaxanthin is able to span the cell membrane, it provides antioxidant protection to the inner and the outer wall, as well as the intra-membrane space.

Of all the carotenoids, astaxanthin is nature’s most potent, with the highest known ORAC value (oxygen radical absorbance capacity) – a measure of its ability to combat oxidative stress. Astaxanthin’s ability to quench free radicals is 6,000 times greater than vitamin C, 800 times that of coenzyme Q10 and 550 times that of vitamin E.

Studies to date show astaxanthin’s ability to reduce and terminate oxidative stress, protect against unwanted inflammation and protect cell structure and function, providing health-enhancing properties in the following areas:

  • Astaxanthin for ageing skin – Skin ageing occurs over time, but the ageing process is accelerated by certain lifestyle factors and exposure to agents which cause oxidative stress in the skin – like, for example smoking, drinking alcohol, UV exposure from the sun and poor diet, amongst others. Studies illustrate that supplementation and topical application of astaxanthin improved the appearance of ‘crow’s feet’, improved elasticity, skin texture and moisture content over the course of 8 weeks (1). Who doesn’t want to keep that fresh-faced and crease-free complexion for longer?
  • Astaxanthin for exercise – Exercise leads to production of reactive oxygen nitrogen species (RONS) within muscle, which promote improvement in athletic performance. Without the body’s own antioxidant capabilities, RONS can cause a state of oxidative stress, the body can become overloaded during times of vigorous exercise, thus leading to oxidation, damaging molecules and potentially a negative impact on physiological function. Astaxanthin is not only a powerful antioxidant, but as it also upregulates the body’s own antioxidant capabilities, it helps to rebalance the oxidative stress caused by an over-production of RONS, with 3-5 weeks of astaxanthin supplementation shown to improve exercise metabolism, performance and recovery (2).
  • Astaxanthin for neuroprotection – Astaxanthin is a fat-soluble molecule, enabling it to pass the blood-brain barrier where it can exert its beneficial effects neurologically. With its ability to upregulate the body’s own antioxidant capabilities, as well as exerting anti-inflammatory effects, supplementing with astaxanthin can reduce the production of reactive oxygen species (ROS), the build-up of which can lead to tissue damage and therefore loss of function following a cerebrovascular event (3).
  • Astaxanthin for cardiovascular disease – Studies suggest that taking astaxanthin before an ischemic event provides protection to the muscle tissue of the heart (4). It has also been shown to have a positive effect on cholesterol levels by decreasing overall triglycerides and increasing HDL (‘good’) cholesterol, which provides protection against atherosclerosis as HDL cholesterol carries LDL (‘bad’) cholesterol back to the liver to prevent it from forming plaques in the arteries (5).
  • Astaxanthin for eye health – Astaxanthin protects the cells of the eye following an ischemic attack (6) and also inhibits retinal damage following white light exposure (7). A 6mg daily dose of astaxanthin for 4 weeks has also been shown to improve the function of the eye in middle-aged participants with eye strain complaints (8).
  • Astaxanthin for immunity – Astaxanthin has been shown to boost the immune response and reduce DNA damage when exposed to infection (9).
  • Introducing Pure Essentials AstaPure Astaxanthin Complex

    Pure Essentials AstaPure Astaxanthin Complex is a natural extract from the microalgae Haematococcus pluvialis (H. Pluvialis) – the same algae responsible for the pink-red pigmentation of wild salmon and crustaceans. AstaPure contains the highest available concentration of astaxanthin, as well as a complex of other beneficial carotenoids including lutein, canthaxanthin, zeaxanthin and beta-carotene, amino acids and fatty acids, which together offer a broad range of health benefits, enhance its bioavailability and increase cell membrane stability.

    Written by Maxine Sheils, Nutritional Therapist at Igennus Healthcare Nutrition.

    References
    1. Tominaga K., Hongo N., Karato M., et al. (2012). ‘Cosmetic benefits of astaxanthin on humans subjects’, Acta biochimica polonic, 59 (1), pp. 43-47.
    2. Brown D. R., Gough L.A., Deb S.K., et al. (2018). ‘Astaxanthin in exercise metabolism, performance and recovery: a review’, Frontiers in nutrition, 4 (76), pp. 1-9.
    3. Haijian W., Huanjiang N., Anwen S., et al. (2015). ‘Astaxanthin as a Potential Neuroprotective Agent for Neurological Diseases’, Marine drugs, 13 (9), pp. 5750-5766.
    4. Fassett R.G. & Coombes J.S. (2011). ‘’Astaxanthin: A Potential Therapeutic Agent in Cardiovascular Disease’, Marine drugs, 9 pp. 447-465.
    5. Yoshida H., Yanai H., Ito K., et al. (2010). ‘Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia’, Atherosclerosis, 209 (2), pp. 520-523. 7.
    6. Otsuka T., Shimazawa M., Inoue Y., et al. (2016). ‘Astaxanthin Protects Against Retinal Damage: Evidence from In Vivo and In Vitro Retinal Ischemia and Reperfusion Models’, Current eye research, 41 (11), pp. 1465-1472.
    7. Tomohiro O., Masamitsu S., Tomohiro N., et al. (2013). ‘The Protective Effects of a Dietary Carotenoid, Astaxanthin, Against Light-Induced Retinal Damage’, Journal of pharmacological sciences’, 123, pp. 209-218.
    8. Kajita M., Tsukahara H. & Kato M. (2009). ‘The Effects of a Dietary Supplement Containing Astaxanthin on the accommodation Function of the Eye in Middle-aged and Older People’, Translated from medical consultation and new remedies, 46 (3), pp. 1-7.
    9. Park J.S., Chyun J.H, Kim Y.K, et al. (2010). ‘Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans’, Nutrition and metabolism, 7 (18) pp. 1-10.

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    Doctor’s Best: CoQ10

    What is Coenzyme Q10?

    Coenzyme Q10 is a vitamin-like, fat soluble nutrient central to energy production at the cellular level, essential for generating metabolic energy in the form of ATP.

    What is ATP?

    ATP is the energy currency of every cell in the human body, it is necessary for not only exercise but for life. ATP is produced in the mitochondria, the power-house of cells, where Coenzymes Q10 plays its role.

    CoQ10 levels and age

    Unfortunately, CoQ10 levels decrease with age. A factor that may actually contribute to the aging process. It is believed that exhaustive, prolonged exercise may further deplete CoQ10 levels. Food content of CoQ10 can be very low, thus many healthcare providers recommend supplementing with Coenzyme Q10. Given CoQ10’s vital role in energy production, supplementation seems to be a wise decision for any athlete engaging in exhaustive exercise.

    Clinical trials on Coenzyme Q10

    Clinical trials have demonstrated Coenzyme Q10’s usefulness as an ergogenic aid, which are substances that benefit athletic performance. One study demonstrated that only 8 weeks of CoQ10 supplementation at 100mg showed performance improvement and fatigue reduction in repeated bouts of exercise compared to placebo (1).
    Another study showed significant improvement in power production in elite, Olympic athletes after 6 weeks of supplementation (2).

    In 2008, a clinical trial showed that CoQ 10 supplementation improved time to exhaustion for participants in only 2 weeks (3).

    CoQ10 and Athletic Performance

    CoQ 10’s use as an ergogenic aid extends beyond its direct improvement of performance markers, it also helps athletes deal with exercise-induced stress. Taking CoQ 10 before strenuous bouts of exercise has been shown to reduce oxidative stress and inflammatory signaling, preventing further damages to the muscles (4).

    Scientific References:

    1. Gökbel H, Gül I, Belviranl M, Okudan N. The effects of coenzyme Q10 supplementation on performance during repeated bouts of supramaximal exercise in sedentary men. J Strength Cond Res. 2010;24(1):97-102.
    2. Alf D, Schmidt ME, Siebrecht SC. Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study. J Int Soc Sports Nutr. 2013;10:24.
    3. Cooke M, Iosia M, Buford T, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008;5:8.
    4. Díaz-castro J, Guisado R, Kajarabille N, et al. Coenzyme Q(10) supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. Eur J Nutr. 2012;51(7):791-9.
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    Magnesium supplementation boosts physical performance in older women

    A new study published last month in the American Journal of Clinical Nutrition indicates that magnesium supplementation can improve physical performance in older women (1).

    Compared with the placebo group, the magnesium group made significant improvements in all measures of physical performance
    “Compared with the placebo group, the magnesium group made significant improvements in all measures of physical performance”

    A focus on healthy ageing is paramount because the UK population is getting older. Currently one-in-six of the UK population is aged 65 and over. By 2050, this number will reach one-in-four. Life expectance is steadily increasing. Unfortunately ‘healthy life expectancy’, or years free from disability, is not increasing at the same rate (2). Good nutrition is a critical component of healthy ageing, allowing us to take charge of our health and remain fit and independent in later life.

    This particular study tested the effect of magnesium on older women’s ability to carry out everyday functional movements such as lifting and carrying, alongside other measures of strength and balance.

    The researchers studied a group of 139 healthy women with an average age of 71. Each of the women underwent a gentle 12-week exercise programme. While half of the women were given a placebo pill, the remainder of the group were given a daily magnesium supplement.

    At the beginning and end of the study, each of the participants were tested for measures of physical performance. Simple functional movements, such as getting out of a chair and balancing tasks, were assessed. Compared with the placebo group, the magnesium group made significant improvements in all measures of physical performance.

    The magnesium group also made ‘substantial’ improvements in walking speed compared to the placebo group. This result was of particular interest to the researchers because walking speed is an independent predictor of adverse health events.

    The benefits of supplementation were most pronounced in those women whose diets were deficient in magnesium. However, improvements were also noted in those whose magnesium intake met the Recommended Daily Allowance.

    As we age, we have a tendency to lose muscle mass. This degenerative loss of muscle mass, known as sarcopenia, robs older people of independence by limiting mobility and the ability safely to carry out simple functional movements. “These findings suggest a role for magnesium supplementation in preventing or delaying the age-related decline in physical performance, particularly in magnesium-deficient individuals”, wrote the researchers.

    Magnesium is involved in more physiological processes than any other mineral. It plays a critical role in energy production, bone and tooth formation, muscle function, cardiovascular health, bowel function and blood sugar regulation.

    Unfortunately the average women in the UK does not manage to obtain the recommended amount of magnesium through her diet, and older women are even more at risk of deficiency (3). Eliminating refined grains, sugar and other processed foods from the diet goes a long way towards ensuring a good intake of magnesium. Magnesium supplements, and increased intake of magnesium-rich leafy greens, beans and lentils, can also help address deficiencies.

    This particular study used magnesium in the form of magnesium oxide, at a dosage of 300mg elemental magnesium. While magnesium oxide is cheap, it is not the most bioavailable form of magnesium. Magnesium citrate or magnesium malate, which demonstrate superior bioavailability, are often considered more helpful by nutritionists.

    References

    1. Veronese N, et al. Effect of oral magnesium supplementation on physical performance in healthy elderly women involved in a weekly exercise program: a randomised controlled trial. American Journal of Clinical Nutrition Epub 9 July 2014
    2. Cracknell R (2010) The ageing population. Key Issues for the New Parliament. House of Commons Library Research.
    3. Food Standard Agency. (2011) National Diet and Nutrition Survey: adults over 65 years.

    Image courtesy of Ambro / FreeDigitalPhotos.net

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    7 Health Benefits of Using Pure Oxygen

    Pure oxygen has been used by hospitals to improve our health for over 200 years and has been recorded to improve our exercise performance since as early as 1928, although the first famous figure was Sir Roger Bannister, who published a research paper about the benefits of using pure oxygen in 1954 (the same year he broke the 4 minute mile).

    Whilst not new, the use of pure oxygen is becoming more widely accepted and more widely understood for the health benefits it can provide. Air contains 21% oxygen and canned oxygen is normally 95%.

    Here are 7 Health benefits of using pure oxygen:

    1. Slow down ageing skin

    From wrinkle creams to moisturising gels to facials, we all want to slow the ageing process. Getting rid of those crow’s feet, laughter lines or frowning tell tale marks, the beauty industry offers every type of product and solution that our heart’s desire. Pure oxygen is starting to break onto the scene to help us in the fight against ageing. Try canned oxygen as part of your daily beauty regime.

    2. Stressful lives

    The 9 to 5 is a challenge for all of us. Trying to get more done in the same amount of hours is best described by the ‘Carrot and Donkey’ fable. From getting to work, wanting to achieve more, dealing with more than one person should, followed by trying to fit enough house time, family time, and me time, can have us at breaking point several times per week. We all know that when we are stressed someone normally suggests ‘taking a deep breath’. Pure oxygen can help you take a moment, get pure oxygen into your bloodstream and help you tackle the road ahead with a little more ease because pure oxygen can help to reduce stress.

    3. Think faster

    A study by the Human cognitive Neuroscience Unit in Northumbria experimented with pure oxygen and concluded that those breathing pure oxygen remembered up to 20% more words, from a given list, than those that did not breathe pure oxygen. If you are struggling some days to focus, get things done, then breathing pure oxygen can help make those tasks that bit easier and quicker.

    4. That jetlag feeling

    Flying on long haul is challenging enough with not enough leg room and then arriving to feel as though all your energy has been left on the plane. The reasons for this are to do with the change in time zone, obviously the long travel, and also the increased pressure in the airplane cabin, which means that less oxygen enters your blood stream. Using pure oxygen will help you to overcome jetlag quickly and help you to enjoy your holiday sooner.

    5. Speeds up recovery

    Footballers, rugby players, and runners, to name a few, are breathing pure oxygen to help them speed up their recovery. Of course, when you earn tens of thousands per week and your team depend on you, or you just want to get back to winning again, speed of recovery is key. Breathing pure oxygen has been prescribed by hospitals for recovery and now breathing pure oxygen can help everyone that is looking to recover more quickly from injury, a minor operation or a period of being unwell.

    Untitled-1
    Air contains 21% oxygen and canned oxygen is normally 95%.

    6. The great detoxer and cleanser

    According to many health gurus the great body cleanser and detoxifier is oxygen. Our lifestyle is less physical than our ancestors and so we are not oxygenating our blood as well as they did, which leads to our bodies carrying more toxins than we did generations before us. Breathing pure oxygen can help to reduce those toxins that we carry in our bodies, in turn helping us to be healthier.

    7. Booost the immune system

    Our immune system helps us to fight infections, diseases, coughs & colds, and helping it do its job is key to living more healthy. There are a number of ways you can maximise your immune system, like eating healthily, exercising regularly, moderating your alcohol, and breathing pure oxygen is another way of helping you to help your immune system to help you.

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    The antioxidant advantage – introducing a new standard in Rosehip Oil

    Trilogy Rosehip Oil Antioxidant+ is here!

    Our busy daily lives see us constantly exposed to free radicals – microscopic organic molecules responsible for ageing and tissue damage. Pollution, sun exposure, diet and stress are just some of the sources of free radicals we deal with every day. They attack skin cells, causing them to break down and so affecting the health and the appearance of our skin.

    Trilogy Rosehip oil Antioxidant+
    Trilogy Rosehip Oil Antioxidant+ is a red berry seed oil blend which provides intensive nourishment.

    Antioxidants provide a counter attack, helping stop free radical damage and providing protection for the skin. This ensures the integrity of healthy cells and helps to maintain a youthful, radiant complexion.

    While our main source of antioxidants is through diet, the body is so hungry for these useful molecules that most of them are absorbed into our systems before they reach the outer layer of the skin. Choosing skincare with high antioxidant content ensures that the skin receives its own supply.

    Trilogy Rosehip Oil Antioxidant+ contains red berry super antioxidants, such as lycopene from tomato and phytosterol from acai berry, providing powerful protection from free radicals and helping to prevent visible signs of premature ageing. Combined with Certified Organic Rosehip Oil, which is high in Essential Fatty Acids and delivers intensive nourishment and hydration to replenish softness and elasticity, these ingredients create the perfect skincare product, one which helps to repair yesterday’s damage and protect from tomorrow’s for healthier younger looking skin.

    Trilogy Rosehip Oil Antioxidant+ is a 100% natural, certified organic red berry seed oil blend – the ‘everything-your-skin-needs’ beauty oil.

    Written by Corinne Morley at Trilogy

    About the Author:

    Corinne Morley is Global Sales and Marketing Manager for New Zealand natural skincare brand Trilogy. A passionate international industry expert, she has a comprehensive beauty background encompassing marketing, sales, training, research and product development, and management roles.


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